diff --git a/changelog.d/5200.bugfix b/changelog.d/5200.bugfix
new file mode 100644
index 000000000..f346c7b0c
--- /dev/null
+++ b/changelog.d/5200.bugfix
@@ -0,0 +1 @@
+Fix worker registration bug caused by ClientReaderSlavedStore being unable to see get_profileinfo.
diff --git a/synapse/app/client_reader.py b/synapse/app/client_reader.py
index 864f1eac4..707f7c2f0 100644
--- a/synapse/app/client_reader.py
+++ b/synapse/app/client_reader.py
@@ -29,6 +29,7 @@ from synapse.http.server import JsonResource
 from synapse.http.site import SynapseSite
 from synapse.metrics import RegistryProxy
 from synapse.metrics.resource import METRICS_PREFIX, MetricsResource
+from synapse.replication.slave.storage import SlavedProfileStore
 from synapse.replication.slave.storage._base import BaseSlavedStore
 from synapse.replication.slave.storage.account_data import SlavedAccountDataStore
 from synapse.replication.slave.storage.appservice import SlavedApplicationServiceStore
@@ -83,6 +84,7 @@ class ClientReaderSlavedStore(
     SlavedTransactionStore,
     SlavedClientIpStore,
     BaseSlavedStore,
+    SlavedProfileStore,
 ):
     pass