diff --git a/changelog.d/13574.bugfix b/changelog.d/13574.bugfix
new file mode 100644
index 000000000..3899c137a
--- /dev/null
+++ b/changelog.d/13574.bugfix
@@ -0,0 +1 @@
+Fix the `opentracing.force_tracing_for_users` config option not applying to [`/sendToDevice`](https://spec.matrix.org/v1.3/client-server-api/#put_matrixclientv3sendtodeviceeventtypetxnid) and [`/keys/upload`](https://spec.matrix.org/v1.3/client-server-api/#post_matrixclientv3keysupload) requests.
\ No newline at end of file
diff --git a/synapse/rest/client/keys.py b/synapse/rest/client/keys.py
index e3f454896..a395694fa 100644
--- a/synapse/rest/client/keys.py
+++ b/synapse/rest/client/keys.py
@@ -26,7 +26,7 @@ from synapse.http.servlet import (
     parse_string,
 )
 from synapse.http.site import SynapseRequest
-from synapse.logging.opentracing import log_kv, set_tag, trace_with_opname
+from synapse.logging.opentracing import log_kv, set_tag
 from synapse.types import JsonDict, StreamToken
 
 from ._base import client_patterns, interactive_auth_handler
@@ -71,7 +71,6 @@ class KeyUploadServlet(RestServlet):
         self.e2e_keys_handler = hs.get_e2e_keys_handler()
         self.device_handler = hs.get_device_handler()
 
-    @trace_with_opname("upload_keys")
     async def on_POST(
         self, request: SynapseRequest, device_id: Optional[str]
     ) -> Tuple[int, JsonDict]:
diff --git a/synapse/rest/client/sendtodevice.py b/synapse/rest/client/sendtodevice.py
index 1a8e9a96d..46a8b0382 100644
--- a/synapse/rest/client/sendtodevice.py
+++ b/synapse/rest/client/sendtodevice.py
@@ -19,7 +19,7 @@ from synapse.http import servlet
 from synapse.http.server import HttpServer
 from synapse.http.servlet import assert_params_in_dict, parse_json_object_from_request
 from synapse.http.site import SynapseRequest
-from synapse.logging.opentracing import set_tag, trace_with_opname
+from synapse.logging.opentracing import set_tag
 from synapse.rest.client.transactions import HttpTransactionCache
 from synapse.types import JsonDict
 
@@ -43,7 +43,6 @@ class SendToDeviceRestServlet(servlet.RestServlet):
         self.txns = HttpTransactionCache(hs)
         self.device_message_handler = hs.get_device_message_handler()
 
-    @trace_with_opname("sendToDevice")
     def on_PUT(
         self, request: SynapseRequest, message_type: str, txn_id: str
     ) -> Awaitable[Tuple[int, JsonDict]]: