diff --git a/synapse/python_dependencies.py b/synapse/python_dependencies.py
index 7052333c1..97b631e60 100644
--- a/synapse/python_dependencies.py
+++ b/synapse/python_dependencies.py
@@ -36,7 +36,7 @@ REQUIREMENTS = {
     "pydenticon": ["pydenticon"],
     "ujson": ["ujson"],
     "blist": ["blist"],
-    "pysaml2>=3.0.0,<4.0.0": ["saml2>=3.0.0,<4.0.0"],
+    "pysaml2>=3.0.0": ["saml2>=3.0.0"],
     "pymacaroons-pynacl": ["pymacaroons"],
     "msgpack-python>=0.3.0": ["msgpack"],
     "phonenumbers>=8.2.0": ["phonenumbers"],