diff --git a/CHANGELOG.md b/CHANGELOG.md
index e6ddfa69..b082e4a7 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -7,6 +7,8 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 ## [Unreleased]
 
+- GUI: Remember acknowledged alerts and do not show them again.
+
 ## [3.0.7] - 2025-10-04
 
 ## [3.0.6] - 2025-10-02
diff --git a/src-gui/src/renderer/components/pages/swap/ApiAlertsBox.tsx b/src-gui/src/renderer/components/pages/swap/ApiAlertsBox.tsx
index cee038f3..0e0a6a39 100644
--- a/src-gui/src/renderer/components/pages/swap/ApiAlertsBox.tsx
+++ b/src-gui/src/renderer/components/pages/swap/ApiAlertsBox.tsx
@@ -1,14 +1,14 @@
 import { Box } from "@mui/material";
 import { Alert, AlertTitle } from "@mui/material";
-import { removeAlert } from "store/features/alertsSlice";
-import { useAppDispatch, useAppSelector } from "store/hooks";
+import { acknowledgeAlert } from "store/features/alertsSlice";
+import { useAlerts, useAppDispatch } from "store/hooks";
 
 export default function ApiAlertsBox() {
-  const alerts = useAppSelector((state) => state.alerts.alerts);
+  const alerts = useAlerts();
   const dispatch = useAppDispatch();
 
-  function onRemoveAlert(id: number) {
-    dispatch(removeAlert(id));
+  function onAcknowledgeAlert(id: number) {
+    dispatch(acknowledgeAlert(id));
   }
 
   if (alerts.length === 0) return null;
@@ -20,7 +20,7 @@ export default function ApiAlertsBox() {
           variant="filled"
           severity={alert.severity}
           key={alert.id}
-          onClose={() => onRemoveAlert(alert.id)}
+          onClose={() => onAcknowledgeAlert(alert.id)}
         >
           <AlertTitle>{alert.title}</AlertTitle>
           {alert.body}
diff --git a/src-gui/src/renderer/store/storeRenderer.ts b/src-gui/src/renderer/store/storeRenderer.ts
index c19fec51..dce48138 100644
--- a/src-gui/src/renderer/store/storeRenderer.ts
+++ b/src-gui/src/renderer/store/storeRenderer.ts
@@ -17,7 +17,7 @@ import { LazyStore } from "@tauri-apps/plugin-store";
 const rootPersistConfig = {
   key: "gui-global-state-store",
   storage: sessionStorage,
-  blacklist: ["settings", "conversations", "logs"],
+  blacklist: ["settings", "conversations", "alerts", "logs"],
 };
 
 // Use Tauri's store plugin for persistent settings
@@ -58,6 +58,12 @@ const conversationsPersistConfig = {
   storage: createTauriStorage(),
 };
 
+// Persist alerts across application restarts
+const alertsPersistConfig = {
+  key: "alerts",
+  storage: createTauriStorage(),
+};
+
 // Create a persisted version of the settings reducer
 const persistedSettingsReducer = persistReducer(
   settingsPersistConfig,
@@ -70,11 +76,18 @@ const persistedConversationsReducer = persistReducer(
   reducers.conversations,
 );
 
+// Create a persisted version of the alerts reducer
+const persistedAlertsReducer = persistReducer(
+  alertsPersistConfig,
+  reducers.alerts,
+);
+
 // Combine all reducers, using the persisted settings reducer
 const rootReducer = combineReducers({
   ...reducers,
   settings: persistedSettingsReducer,
   conversations: persistedConversationsReducer,
+  alerts: persistedAlertsReducer,
 });
 
 // Enable persistence for the entire application state
diff --git a/src-gui/src/store/features/alertsSlice.ts b/src-gui/src/store/features/alertsSlice.ts
index 170c4e61..2df35d82 100644
--- a/src-gui/src/store/features/alertsSlice.ts
+++ b/src-gui/src/store/features/alertsSlice.ts
@@ -1,14 +1,28 @@
 import { createSlice, PayloadAction } from "@reduxjs/toolkit";
 import { Alert } from "models/apiModel";
+import { fnv1a } from "utils/hash";
 
 export interface AlertsSlice {
   alerts: Alert[];
+  /// The ids of the alerts that have been acknowledged
+  /// by the user and should not be shown again
+  acknowledgedAlerts: AcknowledgementKey[];
 }
 
 const initialState: AlertsSlice = {
   alerts: [],
+  acknowledgedAlerts: [],
 };
 
+/// We use the key in combination with the fnv1a hash of the title
+/// to uniquely identify an alert
+///
+/// If the title changes, the hash will change and the alert will be shown again
+interface AcknowledgementKey {
+  id: number;
+  titleHash: string;
+}
+
 const alertsSlice = createSlice({
   name: "alerts",
   initialState,
@@ -16,13 +30,21 @@ const alertsSlice = createSlice({
     setAlerts(slice, action: PayloadAction<Alert[]>) {
       slice.alerts = action.payload;
     },
-    removeAlert(slice, action: PayloadAction<number>) {
-      slice.alerts = slice.alerts.filter(
-        (alert) => alert.id !== action.payload,
-      );
+    acknowledgeAlert(slice, action: PayloadAction<number>) {
+      const alertTitle = slice.alerts.find(
+        (alert) => alert.id === action.payload,
+      )?.title;
+
+      // If we cannot find the alert, we cannot acknowledge it
+      if (alertTitle != null) {
+        slice.acknowledgedAlerts.push({
+          id: action.payload,
+          titleHash: fnv1a(alertTitle),
+        });
+      }
     },
   },
 });
 
-export const { setAlerts, removeAlert } = alertsSlice.actions;
+export const { setAlerts, acknowledgeAlert } = alertsSlice.actions;
 export default alertsSlice.reducer;
diff --git a/src-gui/src/store/hooks.ts b/src-gui/src/store/hooks.ts
index 18c02424..df6db140 100644
--- a/src-gui/src/store/hooks.ts
+++ b/src-gui/src/store/hooks.ts
@@ -30,6 +30,8 @@ import {
   TauriBackgroundProgress,
   TauriBitcoinSyncProgress,
 } from "models/tauriModel";
+import { Alert } from "models/apiModel";
+import { fnv1a } from "utils/hash";
 
 export const useAppDispatch = () => useDispatch<AppDispatch>();
 export const useAppSelector: TypedUseSelectorHook<RootState> = useSelector;
@@ -327,3 +329,17 @@ export function useTotalUnreadMessagesCount(): number {
 
   return totalUnreadCount;
 }
+
+/// Returns all the alerts that have not been acknowledged
+export function useAlerts(): Alert[] {
+  return useAppSelector((state) =>
+    state.alerts.alerts.filter(
+      (alert) =>
+        // Check if there is an acknowledgement with
+        // the same id and the same title hash
+        !state.alerts.acknowledgedAlerts.some(
+          (ack) => ack.id === alert.id && ack.titleHash === fnv1a(alert.title),
+        ),
+    ),
+  );
+}