diff --git a/CMakeLists.txt b/CMakeLists.txt
index 5ec37473c..5fa90173a 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -36,9 +36,9 @@ include(CheckCXXSourceCompiles)
 option(WITH_TESTS "Enable building of unit tests" ON)
 option(WITH_GUI_TESTS "Enable building of GUI tests" OFF)
 option(WITH_DEV_BUILD "Use only for development. Disables/warns about deprecated methods." OFF)
-option(WITH_ASAN "Enable address sanitizer checks (Linux only)" OFF)
+option(WITH_ASAN "Enable address sanitizer checks (Linux / macOS only)" OFF)
 option(WITH_COVERAGE "Use to build with coverage tests (GCC only)." OFF)
-option(WITH_APP_BUNDLE "Enable Application Bundle for OS X" ON)
+option(WITH_APP_BUNDLE "Enable Application Bundle for macOS" ON)
 
 option(WITH_XC_AUTOTYPE "Include Auto-Type." ON)
 option(WITH_XC_HTTP "Include KeePassHTTP and Custom Icon Downloads." OFF)
@@ -110,16 +110,20 @@ endif()
 add_gcc_compiler_cxxflags("-fno-exceptions -fno-rtti")
 add_gcc_compiler_cxxflags("-Wnon-virtual-dtor -Wold-style-cast -Woverloaded-virtual")
 add_gcc_compiler_cflags("-Wchar-subscripts -Wwrite-strings")
+
 if(WITH_ASAN)
-  if(NOT CMAKE_SYSTEM_NAME STREQUAL "Linux")
-      message(FATAL_ERROR "WITH_ASAN is only supported on Linux at the moment.")
+  if(NOT (CMAKE_SYSTEM_NAME STREQUAL "Linux" OR APPLE))
+      message(FATAL_ERROR "WITH_ASAN is only supported on Linux / macOS at the moment.")
   endif()
 
   add_gcc_compiler_flags("-fsanitize=address -DWITH_ASAN")
 
-  if(NOT (CMAKE_COMPILER_IS_GNUCXX AND CMAKE_CXX_COMPILER_VERSION VERSION_LESS 4.9))
-    add_gcc_compiler_flags("-fsanitize=leak -DWITH_LSAN")
+  if(CMAKE_SYSTEM_NAME STREQUAL "Linux")
+    if(NOT (CMAKE_COMPILER_IS_GNUCXX AND CMAKE_CXX_COMPILER_VERSION VERSION_LESS 4.9))
+      add_gcc_compiler_flags("-fsanitize=leak -DWITH_LSAN")
+    endif()
   endif()
+
 endif()
 
 string(TOLOWER "${CMAKE_BUILD_TYPE}" CMAKE_BUILD_TYPE_LOWER)
@@ -216,17 +220,36 @@ if(WITH_TESTS)
   enable_testing()
 endif(WITH_TESTS)
 
-find_package(Qt5Core          5.2 REQUIRED)
-find_package(Qt5Network       5.2 REQUIRED)
-find_package(Qt5Concurrent    5.2 REQUIRED)
-find_package(Qt5Widgets       5.2 REQUIRED)
-find_package(Qt5Test          5.2 REQUIRED)
-find_package(Qt5LinguistTools 5.2 REQUIRED)
-find_package(Qt5Network       5.2 REQUIRED)
-if (UNIX AND NOT APPLE)
-    find_package(Qt5DBus 5.2 REQUIRED)
+if(UNIX AND NOT APPLE)
+  find_package(Qt5 COMPONENTS Core Network Concurrent Widgets Test LinguistTools DBus REQUIRED)
+elseif(APPLE)
+  find_package(Qt5 COMPONENTS Core Network Concurrent Widgets Test LinguistTools REQUIRED
+    HINTS /usr/local/Cellar/qt/*/lib/cmake ENV PATH
+  )
+  find_package(Qt5 COMPONENTS MacExtras
+    HINTS /usr/local/Cellar/qt/*/lib/cmake ENV PATH
+  )
+else()
+  find_package(Qt5 COMPONENTS Core Network Concurrent Widgets Test LinguistTools REQUIRED)
 endif()
+
+if(Qt5Core_VERSION VERSION_LESS "5.2.0")
+  message(FATAL_ERROR "Qt version 5.2.0 or higher is required")
+endif()
+
 set(CMAKE_AUTOMOC ON)
+set(CMAKE_AUTOUIC ON)
+set(CMAKE_AUTORCC ON)
+
+if(APPLE)
+  set(CMAKE_MACOSX_RPATH TRUE)
+  find_program(MACDEPLOYQT_EXE macdeployqt HINTS /usr/local/opt/qt5/bin ENV PATH)
+  if(NOT MACDEPLOYQT_EXE)
+    message(FATAL_ERROR "macdeployqt is required to build in macOS")
+  else()
+    message(STATUS "Using macdeployqt: ${MACDEPLOYQT_EXE}")
+  endif()
+endif()
 
 # Debian sets the the build type to None for package builds.
 # Make sure we don't enable asserts there.
@@ -240,17 +263,8 @@ find_package(ZLIB REQUIRED)
 
 set(CMAKE_REQUIRED_INCLUDES ${ZLIB_INCLUDE_DIR})
 
-check_cxx_source_compiles("
-  #include <zlib.h>
-
-  #if !defined(ZLIB_VERNUM) || (ZLIB_VERNUM < 0x1200)
-      #error zlib 1.2.x or higher is required to use the gzip format
-  #endif
-
-  int main() { return 0; }" ZLIB_SUPPORTS_GZIP)
-
-if(NOT ZLIB_SUPPORTS_GZIP)
-  message(FATAL_ERROR "zlib 1.2.x or higher is required to use the gzip format")
+if(ZLIB_VERSION_STRING VERSION_LESS "1.2.0")
+  message(FATAL_ERROR "zlib 1.2.0 or higher is required to use the gzip format")
 endif()
 
 # Optional
diff --git a/README.md b/README.md
index 669b0b666..e379123c1 100644
--- a/README.md
+++ b/README.md
@@ -70,10 +70,12 @@ cmake accepts the following options:
   -DWITH_TESTS=[ON|OFF] Enable/Disable building of unit tests (default: ON)
   -DWITH_GUI_TESTS=[ON|OFF] Enable/Disable building of GUI tests (default: OFF)
   -DWITH_DEV_BUILD=[ON|OFF] Enable/Disable deprecated method warnings (default: OFF)
-  -DWITH_ASAN=[ON|OFF] Enable/Disable address sanitizer checks (Linux only) (default: OFF)
+  -DWITH_ASAN=[ON|OFF] Enable/Disable address sanitizer checks (Linux / macOS only) (default: OFF)
   -DWITH_COVERAGE=[ON|OFF] Enable/Disable coverage tests (GCC only) (default: OFF)
 ```
 
+:exclamation: When building with ASan support on macOS, you need to use `export ASAN_OPTIONS=detect_leaks=0` before running the tests (no LSan support in macOS).
+
 ### Contributing
 
 We are always looking for suggestions how to improve our application. If you find any bugs or have an idea for a new feature, please let us know by opening a report in our [issue tracker](https://github.com/keepassxreboot/keepassxc/issues) on GitHub or join us on IRC on freenode channels #keepassxc or #keepassxc-dev.
diff --git a/src/CMakeLists.txt b/src/CMakeLists.txt
index bd8a1fd33..3d5e7bf48 100644
--- a/src/CMakeLists.txt
+++ b/src/CMakeLists.txt
@@ -234,6 +234,9 @@ target_link_libraries(keepassx_core
 
 if(APPLE)
     target_link_libraries(keepassx_core "-framework Foundation")
+    if(Qt5MacExtras_FOUND)
+      target_link_libraries(keepassx_core Qt5::MacExtras)
+    endif()
 endif()
 if (UNIX AND NOT APPLE)
     target_link_libraries(keepassx_core Qt5::DBus)
@@ -264,13 +267,7 @@ if(APPLE AND WITH_APP_BUNDLE)
   set_target_properties(${PROGNAME} PROPERTIES
                         MACOSX_BUNDLE ON
                         MACOSX_BUNDLE_INFO_PLIST ${CMAKE_CURRENT_BINARY_DIR}/Info.plist)
-endif()
 
-install(TARGETS ${PROGNAME}
-        BUNDLE DESTINATION . COMPONENT Runtime
-        RUNTIME DESTINATION ${BIN_INSTALL_DIR} COMPONENT Runtime)
-
-if(APPLE AND WITH_APP_BUNDLE)
   if(QT_MAC_USE_COCOA AND EXISTS "${QT_LIBRARY_DIR}/Resources/qt_menu.nib")
     install(DIRECTORY "${QT_LIBRARY_DIR}/Resources/qt_menu.nib"
             DESTINATION "${DATA_INSTALL_DIR}")
@@ -284,16 +281,17 @@ if(APPLE AND WITH_APP_BUNDLE)
   set(CPACK_PACKAGE_FILE_NAME "${PROGNAME}-${KEEPASSXC_VERSION}")
   include(CPack)
 
-  if(NOT DEFINED QT_BINARY_DIR)
-    set(QT_BINARY_DIR "/usr/local/opt/qt5/bin" CACHE PATH "QT binary folder")
-  endif()
   add_custom_command(TARGET ${PROGNAME}
                      POST_BUILD
-                     COMMAND ${QT_BINARY_DIR}/macdeployqt ${PROGNAME}.app
+                     COMMAND ${MACDEPLOYQT_EXE} ${PROGNAME}.app
                      WORKING_DIRECTORY ${CMAKE_BINARY_DIR}/src
                      COMMENT "Deploying app bundle")
 endif()
 
+install(TARGETS ${PROGNAME}
+      BUNDLE DESTINATION . COMPONENT Runtime
+      RUNTIME DESTINATION ${BIN_INSTALL_DIR} COMPONENT Runtime)
+
 if(MINGW)
   if(${CMAKE_SIZEOF_VOID_P} EQUAL "8")
     set(OUTPUT_FILE_POSTFIX "Win64")
diff --git a/src/autotype/mac/CMakeLists.txt b/src/autotype/mac/CMakeLists.txt
index ac93de0e7..08c532784 100644
--- a/src/autotype/mac/CMakeLists.txt
+++ b/src/autotype/mac/CMakeLists.txt
@@ -9,14 +9,12 @@ set(autotype_mac_mm_SOURCES
 add_library(keepassx-autotype-cocoa MODULE ${autotype_mac_SOURCES} ${autotype_mac_mm_SOURCES})
 set_target_properties(keepassx-autotype-cocoa PROPERTIES LINK_FLAGS "-framework Foundation -framework AppKit -framework Carbon")
 target_link_libraries(keepassx-autotype-cocoa ${PROGNAME} Qt5::Core Qt5::Widgets)
-if(NOT DEFINED QT_BINARY_DIR)
-  set(QT_BINARY_DIR "/usr/local/opt/qt5/bin" CACHE PATH "QT binary folder")
-endif()
+
 if(WITH_APP_BUNDLE)
   add_custom_command(TARGET keepassx-autotype-cocoa
                      POST_BUILD
                      COMMAND ${CMAKE_COMMAND} -E copy ${CMAKE_CURRENT_BINARY_DIR}/libkeepassx-autotype-cocoa.so ${PLUGIN_INSTALL_DIR}
-                     COMMAND ${QT_BINARY_DIR}/macdeployqt ${PROGNAME}.app -executable=${PLUGIN_INSTALL_DIR}/libkeepassx-autotype-cocoa.so -no-plugins
+                     COMMAND ${MACDEPLOYQT_EXE} ${PROGNAME}.app -executable=${PLUGIN_INSTALL_DIR}/libkeepassx-autotype-cocoa.so -no-plugins
                      WORKING_DIRECTORY ${CMAKE_BINARY_DIR}/src
   COMMENT "Deploying autotype plugin")
 else()
diff --git a/utils/fix_mac.sh b/utils/fix_mac.sh
deleted file mode 100755
index 2e4e84e5e..000000000
--- a/utils/fix_mac.sh
+++ /dev/null
@@ -1,20 +0,0 @@
-#!/bin/bash
-
-# Canonical path to qt5 directory
-QT="/usr/local/Cellar/qt"
-if [ ! -d "$QT" ]; then
-    # Alternative (old) path to qt5 directory
-    QT+="5"
-    if [ ! -d "$QT" ]; then
-        echo "Qt/Qt5 not found!"
-        exit
-    fi
-fi
-QT5_DIR="$QT/$(ls $QT | sort -r | head -n1)"
-echo $QT5_DIR
-
-# Change qt5 framework ids
-for framework in $(find "$QT5_DIR/lib" -regex ".*/\(Qt[a-zA-Z]*\)\.framework/Versions/5/\1"); do
-    echo "$framework"
-    install_name_tool -id "$framework" "$framework"
-done